Altered Protein in Mice may help with Alzheimer’s and Schizophrenia

Scientists have altered a protein called phosphodiesterase-4B (PDE4B). It may seem like an arbitrary statement to make but this news is gravely important. It may ease the symptoms of Alzheimer’s disease and schizophrenia.


However it may be too early to definitely say whether or not it will actually be an effective treatment for those afflicated with the mentioned diseases. A pharmacologist by the name of Ernesto Fedele of the University of Genoa in Italy has cautioned this as a treatment but believes that it deserves a further investigation into it being an effective treatment.


Alexander McGirr of the University of British Columbia has stated curious behaviours that the mice have exhibited due to their altered protein. The mice, who have been compared with others, have shown that they are more adept at locating things that have been moved and are more familiar with other mice after 24 hours. They also have exhibited signs of “risky” behaviour. They are perfectly okay with being in the presence of bobcat urine, which normally would terrify mice.


McGirr has said that it is very resonable that scientists could develop medicines but effective medicines are long ways away.

-Edward O’Neill

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